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105838-14-0

105838-14-0 structure
105838-14-0 structure

Name [(2-methylpropan-2-yl)oxycarbonylamino] 4-methylbenzenesulfonate
Synonyms TERT-BUTYL TOSYLOXYCARBAMATE
N-Boc-O-tosyl-hydroxylamine
Boc N-tosyloxycarbamate
tert-Butyl N-Tosyloxycarbamate
Description N-Boc-O-tosyl hydroxylamine is used as a linker for antibody-drug conjugates (ADC)[1].
Related Catalog
Target

Alkyl/ether

References

[1]. BOGER, Dale. CHIMER CONTAINING A TARGETING PORTION LINKED TO A SCISSION-ACTIVATED DUOCARMYCIN-TYPE PRODRUG. WO2009064913A1.

Molecular Formula C12H17NO5S
Molecular Weight 287.33200
Exact Mass 287.08300
PSA 93.57000
LogP 3.42520
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H317-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
RIDADR NONH for all modes of transport
HS Code 2924299090

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105838-14-0 structure

105838-14-0

Literature: Greck, Christine; Bischoff, Laurent; Girard, Anne; Hajicek, Josef; Genet, Jean-Pierre Bulletin de la Societe Chimique de France, 1994 , vol. 131, # 4 p. 429 - 433

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105838-14-0 structure

105838-14-0

Literature: Carpino et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 955

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105838-14-0 structure

105838-14-0

Literature: Carpino et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 955

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105838-14-0 structure

105838-14-0

Literature: Molnar, Istvan Gabor; Tanzer, Eva-Maria; Daniliuc, Constantin; Gilmour, Ryan Chemistry - A European Journal, 2014 , vol. 20, # 3 p. 794 - 800
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%