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197142-34-0

197142-34-0 structure
197142-34-0 structure
  • Name: N-Boc-L-trans-4,5-methanoproline
  • Chemical Name: (1R,3S,5R)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
  • CAS Number: 197142-34-0
  • Molecular Formula: C11H17NO4
  • Molecular Weight: 227.257
  • Create Date: 2018-12-31 12:53:21
  • Modify Date: 2024-01-12 18:02:59

Name (1R,3S,5R)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Synonyms (1R,3S,5R)-2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
N-Boc-L-trans-4,5-methanoproline
(1R,3S,5R)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
(1R,3S,5R)-2-aza-bicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester
2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) ester, (1R,3S,5R)-
(1R,3S,5R)-2-tert-butoxycarbonyl-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
(4R,5R)-metano-N-Boc-L-proline
Density 1.3±0.1 g/cm3
Boiling Point 355.9±25.0 °C at 760 mmHg
Molecular Formula C11H17NO4
Molecular Weight 227.257
Flash Point 169.0±23.2 °C
Exact Mass 227.115753
PSA 66.84000
LogP 0.41
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.537

~75%

197142-34-0 structure

197142-34-0

Literature: Hanessian, Stephen; Reinhold, Ulrich; Gentile, Gabriella Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 17 p. 1881 - 1884

~76%

197142-34-0 structure

197142-34-0

Literature: BRISTOL-MYERS SQUIBB COMPANY; PACK, Shawn, K.; TYMONKO, Steven; PATEL, Bharat, P.; NATALIE, JR., Kenneth, J.; BELEMA, Makonen Patent: WO2011/59850 A1, 2011 ; Location in patent: Page/Page column 179-180 ;

~60%

197142-34-0 structure

197142-34-0

Literature: BRISTOL-MYERS SQUIBB COMPANY; PACK, Shawn, K.; TYMONKO, Steven; PATEL, Bharat, P.; NATALIE, JR., Kenneth, J.; BELEMA, Makonen Patent: WO2011/59850 A1, 2011 ; Location in patent: Page/Page column 178-179 ;

~%

197142-34-0 structure

197142-34-0

Literature: Hanessian, Stephen; Reinhold, Ulrich; Gentile, Gabriella Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 17 p. 1881 - 1884

~%

197142-34-0 structure

197142-34-0

Literature: BRISTOL-MYERS SQUIBB COMPANY; PACK, Shawn, K.; TYMONKO, Steven; PATEL, Bharat, P.; NATALIE, JR., Kenneth, J.; BELEMA, Makonen Patent: WO2011/59850 A1, 2011 ;

~%

197142-34-0 structure

197142-34-0

Literature: BRISTOL-MYERS SQUIBB COMPANY; PACK, Shawn, K.; TYMONKO, Steven; PATEL, Bharat, P.; NATALIE, JR., Kenneth, J.; BELEMA, Makonen Patent: WO2011/59850 A1, 2011 ;

~%

197142-34-0 structure

197142-34-0

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; THIBEAULT, Carl; EDWARDS, Paul, J.; KUHN, Cyrille; MOREAU, BenoIt; POIRIER, Maude; SURPRENANT, Simon Patent: WO2012/48421 A1, 2012 ;

~%

197142-34-0 structure

197142-34-0

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; THIBEAULT, Carl; EDWARDS, Paul, J.; KUHN, Cyrille; MOREAU, BenoIt; POIRIER, Maude; SURPRENANT, Simon Patent: WO2012/48421 A1, 2012 ;

~%

197142-34-0 structure

197142-34-0

Literature: BRISTOL-MYERS SQUIBB COMPANY; PACK, Shawn, K.; TYMONKO, Steven; PATEL, Bharat, P.; NATALIE, JR., Kenneth, J.; BELEMA, Makonen Patent: WO2011/59850 A1, 2011 ;