196961-43-0
196961-43-0 structure
- Name: CD 3254
- Chemical Name: 3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)phenyl]prop-2-enoic acid
- CAS Number: 196961-43-0
- Molecular Formula: C24H28O3
- Molecular Weight: 364.47700
- Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
- Create Date: 2016-04-25 13:52:07
- Modify Date: 2024-01-04 19:20:18
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CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1].
| Name | 3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)phenyl]prop-2-enoic acid |
|---|
| Description | CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1]. |
|---|---|
| Related Catalog | |
| Target |
RXR |
| In Vitro | CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L)[1]. Cell Viability Assay[1] Cell Line: zebrafish (Danio rerio) embryos Concentration: 10, 20, 50, 100 μg/L Incubation Time: Result: The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day. |
| References |
| Molecular Formula | C24H28O3 |
|---|---|
| Molecular Weight | 364.47700 |
| Exact Mass | 364.20400 |
| PSA | 57.53000 |
| LogP | 5.81440 |