1347750-79-1

1347750-79-1 structure
1347750-79-1 structure
  • Name: HS-PEG3-CH2CH2N3
  • Chemical Name: 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethanethiol
  • CAS Number: 1347750-79-1
  • Molecular Formula: C8H17N3O3S
  • Molecular Weight: 235.30400
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-01-14 06:08:45
  • Modify Date: 2024-01-10 20:03:04
  • HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethanethiol
Description HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C8H17N3O3S
Molecular Weight 235.30400
Exact Mass 235.09900
PSA 116.24000
LogP 0.72906
Precursor  0

DownStream  1