18829-83-9

18829-83-9 structure

Name: 3’-Deoxy-5-fluorouridine
Chemical Name: 5-Fluoro-3'-deoxyuridine
CAS Number: 18829-83-9
Molecular Formula: C₉H₁₁FN₂O₅
Molecular Weight: 246.19
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-10-03 00:40:01
Modify Date: 2024-02-12 19:11:46
3’-Deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-Fluoro-3'-deoxyuridine
Synonyms	5-Fluor-3'-desoxyuridin 5-fluoro-3'-deoxyuridine 3'-deoxy-5-fluorouridine 5-fluoro-3'-deoxy-uridine 1-(3-Deoxy-β-D-erythro-pentofuranosyl)-5-fluorouracil

Description	3’-Deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.