Top Suppliers:I want be here


  • DC Chemicals Limited
  • China
  • Product Name: Triclopyr
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


55335-06-3

55335-06-3 structure
55335-06-3 structure
  • Name: Triclopyr
  • Chemical Name: trichlopyr
  • CAS Number: 55335-06-3
  • Molecular Formula: C7H4Cl3NO3
  • Molecular Weight: 256.471
  • Catalog: Chemical pesticide herbicide Other herbicides
  • Create Date: 2018-06-19 22:32:07
  • Modify Date: 2024-01-02 09:31:26
  • Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity[1].

Name trichlopyr
Synonyms Acetic acid, 2-[(3,5,6-trichloro-2-pyridinyl)oxy]-
Acetic acid, [(3,5,6-trichloro-2-pyridinyl)oxy]-
Rely
Garlon
Caswell No. 882I
Timbrel
[(3,5,6-Trichloro-2-pyridinyl)oxy]acetic acid
EINECS 259-597-3
Exetor
Mutan
3,5,6-trichloro-2-pyridyloxyacetic acid
Remedy
TRIDENT
MFCD00072514
Triclopyr
3,5,6-trichloropyrid-2-yloxyacetic acid
2-[(3,5,6-trichloro-2-pyridinyl)oxy]acetic acid
T6NJ BO1VQ CG EG FG
3,5,6-trichloro-pyridin-2-yl-oxyacetic acid
Curtail
Redeem
M 3724
[(3,5,6-Trichloropyridin-2-yl)oxy]acetic acid
Description Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity[1].
Related Catalog
In Vitro Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells[1]. Cell Cytotoxicity Assay[1] Cell Line: Mouse neuroblastoma (N2a) cells Concentration: 3 mM Incubation Time: 48 hours Result: Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells.
In Vivo Pharmacokinetic Analysis Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) [2]. Animal Model: 3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey [2] Dosage: 0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey) Administration: Oral gavage (beagle dog); intravenous (rhesus monkey) Result: T1/2s of 25 and 6.3 h for dogs and a monkey, respectively.
References

[1]. Tejaswini P Reddy, et al. Toxicity of neurons treated with herbicides and neuroprotection by mitochondria-targeted antioxidant SS31. Int J Environ Res Public Health. 2011 Jan;8(1):203-21.

[2]. C Timchalk, et al. Pharmacokinetics of triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) in the beagle dog and rhesus monkey: perspective on the reduced capacity of dogs to excrete this organic acid relative to the rat, monkey, and human. Toxicol Appl Pharmacol. 1997 Jun;144(2):268-78.

Density 1.7±0.1 g/cm3
Boiling Point 359.1±37.0 °C at 760 mmHg
Melting Point 148-150°C
Molecular Formula C7H4Cl3NO3
Molecular Weight 256.471
Flash Point 171.0±26.5 °C
Exact Mass 254.925674
PSA 59.42000
LogP 2.98
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.591

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ9000000
CHEMICAL NAME :
Acetic acid, (3,5,6-trichloro-2-pyridyloxy)-
CAS REGISTRY NUMBER :
55335-06-3
BEILSTEIN REFERENCE NO. :
0225301
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C7-H4-Cl3-N-O3
MOLECULAR WEIGHT :
256.47
WISWESSER LINE NOTATION :
T6NJ BO1VQ CG EG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
630 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C310,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,844,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,844,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,844,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
1693 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DOEAAH Down to Earth. (Dow Chemical USA, Agricultural Products Dept., Midland, MI 48640) V.1- 1945- Volume(issue)/page/year: 35,25,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1820 mg/kg/13W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 5,1,1985 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1550 mg/kg
SEX/DURATION :
multigenerations
TOXIC EFFECTS :
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,872,1984
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2 gm/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,872,1984 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
RTECS AJ9000000
HS Code 3808931100

~91%

55335-06-3 structure

55335-06-3

Literature: EXCEL CROP CARE LIMITED; C C SHROFF RESEARCH INSTITUTE; AIMCO PESTICIDES LIMITED; SHROFF, Dipesh, Kantisen; SHROFF, Ashwin, Champraj; DAVE, Samir, Pradip Patent: WO2010/23679 A2, 2010 ; Location in patent: Page/Page column 9; 10 ;

~95%

55335-06-3 structure

55335-06-3

Literature: EXCEL CROP CARE LIMITED; C C SHROFF RESEARCH INSTITUTE; AIMCO PESTICIDES LIMITED; SHROFF, Dipesh, Kantisen; SHROFF, Ashwin, Champraj; DAVE, Samir, Pradip Patent: WO2010/23679 A2, 2010 ; Location in patent: Page/Page column 6-7 ;

~%

55335-06-3 structure

55335-06-3

Literature: Journal of Organic Chemistry, , vol. 23, p. 1614
HS Code 2933399028
Summary 2933399028 2-((3,5,6-trichloropyridin-2-yl)oxy)acetic acid。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%