Name | trichlopyr |
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Synonyms |
Acetic acid, 2-[(3,5,6-trichloro-2-pyridinyl)oxy]-
Acetic acid, [(3,5,6-trichloro-2-pyridinyl)oxy]- Rely Garlon Caswell No. 882I Timbrel [(3,5,6-Trichloro-2-pyridinyl)oxy]acetic acid EINECS 259-597-3 Exetor Mutan 3,5,6-trichloro-2-pyridyloxyacetic acid Remedy TRIDENT MFCD00072514 Triclopyr 3,5,6-trichloropyrid-2-yloxyacetic acid 2-[(3,5,6-trichloro-2-pyridinyl)oxy]acetic acid T6NJ BO1VQ CG EG FG 3,5,6-trichloro-pyridin-2-yl-oxyacetic acid Curtail Redeem M 3724 [(3,5,6-Trichloropyridin-2-yl)oxy]acetic acid |
Description | Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity[1]. |
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Related Catalog | |
In Vitro | Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells[1]. Cell Cytotoxicity Assay[1] Cell Line: Mouse neuroblastoma (N2a) cells Concentration: 3 mM Incubation Time: 48 hours Result: Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells. |
In Vivo | Pharmacokinetic Analysis Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) [2]. Animal Model: 3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey [2] Dosage: 0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey) Administration: Oral gavage (beagle dog); intravenous (rhesus monkey) Result: T1/2s of 25 and 6.3 h for dogs and a monkey, respectively. |
References |
Density | 1.7±0.1 g/cm3 |
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Boiling Point | 359.1±37.0 °C at 760 mmHg |
Melting Point | 148-150°C |
Molecular Formula | C7H4Cl3NO3 |
Molecular Weight | 256.471 |
Flash Point | 171.0±26.5 °C |
Exact Mass | 254.925674 |
PSA | 59.42000 |
LogP | 2.98 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |
Index of Refraction | 1.591 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn:Harmful; |
Risk Phrases | R22 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
RTECS | AJ9000000 |
HS Code | 3808931100 |
~91% 55335-06-3 |
Literature: EXCEL CROP CARE LIMITED; C C SHROFF RESEARCH INSTITUTE; AIMCO PESTICIDES LIMITED; SHROFF, Dipesh, Kantisen; SHROFF, Ashwin, Champraj; DAVE, Samir, Pradip Patent: WO2010/23679 A2, 2010 ; Location in patent: Page/Page column 9; 10 ; |
~95% 55335-06-3 |
Literature: EXCEL CROP CARE LIMITED; C C SHROFF RESEARCH INSTITUTE; AIMCO PESTICIDES LIMITED; SHROFF, Dipesh, Kantisen; SHROFF, Ashwin, Champraj; DAVE, Samir, Pradip Patent: WO2010/23679 A2, 2010 ; Location in patent: Page/Page column 6-7 ; |
~% 55335-06-3 |
Literature: Journal of Organic Chemistry, , vol. 23, p. 1614 |
Precursor 4 | |
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DownStream 0 |
HS Code | 2933399028 |
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Summary | 2933399028 2-((3,5,6-trichloropyridin-2-yl)oxy)acetic acid。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0% |