Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Arg-Gly-Glu-Ser?
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

GL Biochem (Shanghai) Ltd.
China
Product Name: R-G-E-S
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Nanjing Peptide Biotech Ltd
China
Product Name: R-G-E-S
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: H-ARG-GLY-GLU-SER-OH
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

93674-97-6

93674-97-6 structure

93674-97-6 structure

Name: R-G-E-S
Chemical Name: h-arg-gly-glu-ser-oh
CAS Number: 93674-97-6
Molecular Formula: C₁₆H₂₉N₇O₈
Molecular Weight: 447.44400
Catalog: Peptides
Create Date: 2017-05-13 19:35:26
Modify Date: 2024-01-03 16:30:38
Arg-Gly-Glu-Ser is a RGD-related peptide and a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets.

Name	h-arg-gly-glu-ser-oh
Synonyms	ARG-GLY-GLU-SER rgespeptide R-G-E-S

Description	Arg-Gly-Glu-Ser is a RGD-related peptide and a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Peptides
In Vivo	Arg-Gly-Glu-Ser (5 mg/kg) in combination with LPS or saline + RGDS does not affect neutrophil and macrophage cell numbers and has no effect on protein accumulation compared with LPS- or saline-treated mice, respectively[1].
Animal Admin	Mice[1] Mouse pharyngeal aspiration is performed in the assay. Animals are anesthetized with a mixture of ketamine and xylazine (45 mg/kg and 8 mg/kg, i.p., respectively). Test solution (30 μL) containing LPS (1.5 mg/kg) is placed posterior in the throat and aspirated into the lungs. Control mice are administrated sterile saline (0.9% NaCl). Animals are administered with RGDS or Arg-Gly-Glu-Ser peptide (1, 2.5 or 5 mg/kg, i.p.) once one hour before LPS treatment and sacrificed 4 h post-LPS. Animals are also administered RGDS or Arg-Gly-Glu-Ser peptide (5 mg/kg, i.p.) once at different time points (1 h before or 2 h after LPS treatment) and sacrificed 24 h post-LPS. In addition, animals are administered with αvβ3-blocking mAbs, anti-αv, or anti-β3 (5 mg/kg, i.p.) once 1 h before and sacrificed 4 h post-LPS. Animals administered with these mAbs 2 h after LPS treatment are sacrificed 24 h post-LPS[1].
References	[1]. Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18.

Density	1.61g/cm3
Molecular Formula	C₁₆H₂₉N₇O₈
Molecular Weight	447.44400
Exact Mass	447.20800
PSA	270.05000
Index of Refraction	1.649
Storage condition	2-8℃

WGK Germany	3