Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 4-Formamidoantipyrine
Price: ￥486.0/250mg ￥1246.0/1g ￥4106.0/5g
Purity: 95.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 4-Formylaminoantipyrine
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Formamide,N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1672-58-8

1672-58-8 structure

1672-58-8 structure

Name: 4-Formamidoantipyrine
Chemical Name: 4-formylaminoantipyrine
CAS Number: 1672-58-8
Molecular Formula: C₁₂H₁₃N₃O₂
Molecular Weight: 231.251
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2018-06-25 10:49:33
Modify Date: 2024-01-02 08:25:48
4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1].

Name	4-formylaminoantipyrine
Synonyms	4-formylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)carboxamide (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imidoformic acid 4-Formylaminoantipyrine Methanimidic acid, (2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylformamide 4-Formamidoantipyrine Formamide,N-antipyrinyl N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)formamide 4-formyl-aminoantipyrin Formamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- 4-Formylaminoantipyrine (N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide 4-formaminoantipyrine N-Formyl-4-aminoantipyrine

Description	4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther [2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31. [3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79.

Density	1.2±0.1 g/cm3
Boiling Point	374.5±52.0 °C at 760 mmHg
Melting Point	189-192ºC
Molecular Formula	C₁₂H₁₃N₃O₂
Molecular Weight	231.251
Flash Point	180.3±30.7 °C
Exact Mass	231.100784
PSA	56.03000
LogP	0.41
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.609
Storage condition	Refrigerator

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Hazard Codes	Xn
Risk Phrases	20/22
RIDADR	NONH for all modes of transport
HS Code	2933199090

64-18-6 structure

64-18-6

83-07-8 structure

83-07-8

~77%

1672-58-8 structure

1672-58-8

Literature: Lopez-Munoz, Francisco Javier; Soria-Arteche, Olivia; Lopez, Jose Raul Medina; Hurtado Y De La Pena, Marcela; Garcia, Ma. Concepcion Lozada; Moreno-Rocha, Luis Alfonso; Dominguez-Ramirez, Adriana Miriam Drug Development Research, 2013 , vol. 74, # 5 p. 332 - 338

885-11-0 structure

885-11-0

~%

1672-58-8 structure

1672-58-8

Literature: Justus Liebigs Annalen der Chemie, , vol. 293, p. 66

Precursor 3
64-18-6 83-07-8 885-11-0
DownStream 0

HS Code	2933199090
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%