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  • DC Chemicals Limited
  • China
  • Product Name: CAY10590
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Tony Cao

1101136-50-8

1101136-50-8 structure
1101136-50-8 structure

Name (R)-4-(7-phenylheptanamido)octanoic acid
Synonyms Octanoic acid, 4-[(1-oxo-7-phenylheptyl)amino]-, (4R)-
(4R)-4-[(7-Phenylheptanoyl)amino]octanoic acid
Description CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases[1].
Related Catalog
Target

sPLA2

In Vitro CAY10590 (GK115) (0-10 μM; 24 h) inhibits IL-1β/forskolin-stimulated PGE2 formation in mesangial cells[1].
References

[1]. Vasilakaki S, et al. Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells. Molecules. 2018 Jan 13;23(1):158.

Density 1.0±0.1 g/cm3
Boiling Point 567.8±43.0 °C at 760 mmHg
Molecular Formula C21H33NO3
Molecular Weight 347.492
Flash Point 297.2±28.2 °C
Exact Mass 347.246033
PSA 66.40000
LogP 4.55
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.511

~90%

1101136-50-8 structure

1101136-50-8

Literature: Antonopoulou, Georgia; Barbayianni, Efrosini; Magrioti, Victoria; Cotton, Naomi; Stephens, Daren; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 24 p. 10257 - 10269
Precursor  1

DownStream  0