Name | (R)-4-(7-phenylheptanamido)octanoic acid |
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Synonyms |
Octanoic acid, 4-[(1-oxo-7-phenylheptyl)amino]-, (4R)-
(4R)-4-[(7-Phenylheptanoyl)amino]octanoic acid |
Description | CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases[1]. |
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Related Catalog | |
Target |
sPLA2 |
In Vitro | CAY10590 (GK115) (0-10 μM; 24 h) inhibits IL-1β/forskolin-stimulated PGE2 formation in mesangial cells[1]. |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 567.8±43.0 °C at 760 mmHg |
Molecular Formula | C21H33NO3 |
Molecular Weight | 347.492 |
Flash Point | 297.2±28.2 °C |
Exact Mass | 347.246033 |
PSA | 66.40000 |
LogP | 4.55 |
Vapour Pressure | 0.0±1.6 mmHg at 25°C |
Index of Refraction | 1.511 |
~90% 1101136-50-8 |
Literature: Antonopoulou, Georgia; Barbayianni, Efrosini; Magrioti, Victoria; Cotton, Naomi; Stephens, Daren; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 24 p. 10257 - 10269 |
Precursor 1 | |
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DownStream 0 |