134332-50-6

134332-50-6 structure

Name: Galanthamine 10-Oxide(Galanthamine N-Oxide)
Chemical Name: Galanthamine N-Oxide
CAS Number: 134332-50-6
Molecular Formula: C₁₇H₂₁NO₄
Molecular Weight: 303.35300
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2016-03-02 16:37:04
Modify Date: 2024-01-21 13:08:21
Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].

Name	Galanthamine N-Oxide
Synonyms	Nivalin-oxide (4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide galanthamine-N-oxide Galanthamine 10-Oxide N-Oxide Galantamine Galanthamine \|A-N-oxide

Description	Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33. [2]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

Hazard Codes	Xi

357-70-0

134332-50-6

60755-80-8

134332-50-6

Literature: Phytochemistry (Elsevier), , vol. 30, # 2 p. 675 - 677

186581-53-3

134332-51-7

134332-50-6