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3428-24-8

3428-24-8 structure
3428-24-8 structure
  • Name: 4,5-Dichlorocatechol
  • Chemical Name: 4,5-dichlorobenzene-1,2-diol
  • CAS Number: 3428-24-8
  • Molecular Formula: C6H4Cl2O2
  • Molecular Weight: 179.001
  • Catalog: Research Areas Infection
  • Create Date: 2018-09-13 12:37:28
  • Modify Date: 2024-01-13 12:08:05
  • 4,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71. The Ki values for 4,5-dichlorocatechol is 30 nM for the dioxygenase of the Chlorobenzoate-degrading strain Pseudomonas putida AC27 and 4 nM for the dioxygenase of Acidovorax sp. strain PS14[1].

Name 4,5-dichlorobenzene-1,2-diol
Synonyms Pyrocatechol,4,5-dichloro
4,5-DICHLOROCATECHOL
4,5-dichloroguaiacol
1,2-Benzenediol,4,5-dichloro
1,2-Benzenediol, 4,5-dichloro-
4,5-Dichloropyrocatechol
4,5-Dichloro-1,2-benzenediol
EINECS 222-331-1
MFCD00463757
4,5-dichlorobenzene-1,2-diol
Description 4,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71. The Ki values for 4,5-dichlorocatechol is 30 nM for the dioxygenase of the Chlorobenzoate-degrading strain Pseudomonas putida AC27 and 4 nM for the dioxygenase of Acidovorax sp. strain PS14[1].
Related Catalog
References

[1]. T Potrawfke , et al. Chlorocatechols Substituted at Positions 4 and 5 Are Substrates of the Broad-Spectrum Chlorocatechol 1,2-dioxygenase of Pseudomonas Chlororaphis RW71. J Bacteriol. 2001 Feb;183(3):997-1011.

Density 1.6±0.1 g/cm3
Boiling Point 302.2±37.0 °C at 760 mmHg
Melting Point 110-115ºC(lit.)
Molecular Formula C6H4Cl2O2
Molecular Weight 179.001
Flash Point 136.6±26.5 °C
Exact Mass 177.958832
PSA 40.46000
LogP 3.29
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.642
Storage condition -20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UX1510000
CHEMICAL NAME :
Pyrocatechol, 4,5-dichloro-
CAS REGISTRY NUMBER :
3428-24-8
BEILSTEIN REFERENCE NO. :
2086136
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H4-Cl2-O2
MOLECULAR WEIGHT :
179.00
WISWESSER LINE NOTATION :
QR BQ DG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
42 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
75 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 119,273,1983
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H315-H319-H335-H400
Precautionary Statements P261-P273-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases S26;S36
RIDADR UN 3077 9 / PGIII
RTECS UX1510000
HS Code 2908199090
HS Code 2908199090
Summary HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%