76296-71-4

76296-71-4 structure

Name: Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.
Chemical Name: (3β,25R)-Spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-g lucopyranoside
CAS Number: 76296-71-4
Molecular Formula: C₃₉H₆₂O₁₂
Molecular Weight: 722.902
Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
Create Date: 2017-07-30 06:26:37
Modify Date: 2024-01-03 17:31:07
Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities[1][2].

Name	(3β,25R)-Spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-g lucopyranoside
Synonyms	PolyphyllinC (3β,25R)-Spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl 3-O-(6-deoxy-α-L-mannopyranosyl)-

Description	Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	IC50: 36.87 µM (tyrosinase)[1]
References	[1]. Devkota KP, et, al. Tyrosinase inhibitory and antileishmanial constituents from the rhizomes of Paris polyphylla. Nat Prod Res. 2007 Apr;21(4):321-7. [2]. Singh SB, et, al. Spirostanol saponins from Paris polyphylla, structures of polyphyllin C, D, E and F. Phytochemistry.1980; 21(12): 2925-2929.

Hazard Codes	Xi