1346112-79-5

1346112-79-5 structure

Name: Thromboxane B2-d4
Chemical Name: (5Z,9β,13E,15S)-9,11,15-Trihydroxy(3,3,4,4-2H4)thromboxa-5,13-dien-1-oic acid
CAS Number: 1346112-79-5
Molecular Formula: C₂₀H₃₀D₄O₆
Molecular Weight: 374.50500
Catalog: Research Areas Inflammation/Immunology
Create Date: 2016-02-20 13:47:59
Modify Date: 2024-01-10 18:09:00
Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation[1][2].

Name	(5Z,9β,13E,15S)-9,11,15-Trihydroxy(3,3,4,4-2H4)thromboxa-5,13-dien-1-oic acid

Description	Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.