176796-64-8

176796-64-8 structure

Name: (RS)-3,4-DCPG
Chemical Name: 4-[amino(carboxy)methyl]phthalic acid
CAS Number: 176796-64-8
Molecular Formula: C₁₀H₉NO₆
Molecular Weight: 239.18
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2017-06-01 12:36:44
Modify Date: 2024-02-01 19:55:08
(R,S)-3,4-Dicarboxyphenylglycine ((RS)-3,4-DCPG) is an AMPA receptor antagonist. (R,S)-3,4-Dicarboxyphenylglycine antagonizes AMPA-mediated depolarization of motor neurons in neonatal rats. (R,S)-3,4-Dicarboxyphenylglycine can be used in the study of neurological diseases[1].

Name	4-[amino(carboxy)methyl]phthalic acid
Synonyms	pacap 1-27 hms3267f06

Description	(R,S)-3,4-Dicarboxyphenylglycine ((RS)-3,4-DCPG) is an AMPA receptor antagonist. (R,S)-3,4-Dicarboxyphenylglycine antagonizes AMPA-mediated depolarization of motor neurons in neonatal rats. (R,S)-3,4-Dicarboxyphenylglycine can be used in the study of neurological diseases[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	AMPA[1].
References	[1]. Thomas NK, et al. Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur J Pharmacol. 1997 Nov 5;338(2):111-6.