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18265-46-8

18265-46-8 structure
18265-46-8 structure
  • Name: D-Ribose 5-phosphate disodium
  • Chemical Name: d-ribose-5-phosphate disodium salt
  • CAS Number: 18265-46-8
  • Molecular Formula: C5H9Na2O8P
  • Molecular Weight: 274.073
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-06-13 19:29:15
  • Modify Date: 2024-01-06 12:37:12
  • D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate disodium is used in the synthesis of nucleotides and nucleic acids[1].

Name d-ribose-5-phosphate disodium salt
Synonyms D-Ribose 5-phosphoric acid disodium salt
D-Ribose 5-phosphate disodium salt
RIBOSE-5-PHOSPHATE SODIUM SALT
D-Ribose-5-phosphate disodium salt hydrate
Disodium (2R,3R,4R)-4-hydroxy-1-oxo-5-(phosphonooxy)-2,3-pentanediolate
sodium ribose-5-phosphate
D-Ribose, 5-(dihydrogen phosphate), sodium salt (1:2)
D-RIBOSE-5-PHOSPHATE,SODIUM SALT
MFCD00005362
Disodium 5-O-phosphonato-D-ribose
EINECS 242-140-7
D-RIBOFURANOSE 5-PHOSPHATE DISODIUM SALT
D-RIBOSE-5-PHOSPHORIC ACID SODIUM SALT
R-5-P-NA2
D-RIBOSE 5-PHOSPHATE DISODIUM
Description D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate disodium is used in the synthesis of nucleotides and nucleic acids[1].
Related Catalog
In Vitro Ribose-5-phosphate is generally assumed to arise via the oxidative and nonoxidative pentose phosphate pathways[1].
References

[1]. Grochowski LL, et al. Ribose-5-phosphate biosynthesis in Methanocaldococcus jannaschii occurs in the absence of a pentose-phosphate pathway. J Bacteriol. 2005 Nov;187(21):7382-9.

Boiling Point 539.9ºC at 760mmHg
Molecular Formula C5H9Na2O8P
Molecular Weight 274.073
Flash Point 280.3ºC
Exact Mass 273.983032
PSA 159.99000
Appearance powder | white
Vapour Pressure 6.58E-14mmHg at 25°C
Storage condition −20°C
Water Solubility H2O: 50 mg/mL, clear, colorless | Soluble in water at 50mg/ml
Name: D-Ribose-5-Phosphate Disodium Salt Hydrate 95% Material Safety Data Sheet
Synonym: None Known
CAS: 18265-46-8
Section 1 - Chemical Product MSDS Name:D-Ribose-5-Phosphate Disodium Salt Hydrate 95% Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
18265-46-8 D-Ribose-5-Phosphate Disodium Salt Hyd 95% 242-140-7
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Deep freeze (below -20C). Store protected from moisture.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 18265-46-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: white to light yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble in water
Specific Gravity/Density:
Molecular Formula: C5H9Na2O8P.xH2O
Molecular Weight: 274.0116

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents, moisture.
Hazardous Decomposition Products:
Carbon monoxide, oxides of phosphorus, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 18265-46-8 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
D-Ribose-5-Phosphate Disodium Salt Hydrate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 18265-46-8: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 18265-46-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 18265-46-8 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi
Safety Phrases S22-S24/25
WGK Germany 3
HS Code 2919900090
HS Code 2919900090
Summary 2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%