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851371-22-7

851371-22-7 structure
851371-22-7 structure
  • Name: (4'-Furan-2-yl-[4,5']bipyrimidinyl-2'-yl)-pyridin-3-yl-amine
  • Chemical Name: 4-(furan-2-yl)-N-pyridin-3-yl-5-pyrimidin-4-ylpyrimidin-2-amine
  • CAS Number: 851371-22-7
  • Molecular Formula: C17H12N6O
  • Molecular Weight: 316.32
  • Create Date: 2018-12-28 08:33:22
  • Modify Date: 2024-01-03 17:49:20
  • LAS38096 is a potent, selective, and efficacious A2B Adenosine Receptor antagonist, with a Ki of 17 nM[1].

Name 4-(furan-2-yl)-N-pyridin-3-yl-5-pyrimidin-4-ylpyrimidin-2-amine
Synonyms Kinome_3729
[4,5'-Bipyrimidin]-2'-amine,4'-(2-furanyl)-N-3-pyridinyl
4'-(Furan-2-yl)-N-(pyridin-3-yl)-[4,5'-bipyrimidin]-2'-amine
Description LAS38096 is a potent, selective, and efficacious A2B Adenosine Receptor antagonist, with a Ki of 17 nM[1].
Related Catalog
Target

A2B:17 nM (Ki)

A1:>1000 nM (Ki)

A2A:>2500 nM (Ki)

A3:>1000 nM (Ki)

References

[1]. Bernat Vidal, et al. Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist. J Med Chem. 2007 May 31;50(11):2732-6.  

Molecular Formula C17H12N6O
Molecular Weight 316.32
Exact Mass 316.10700
PSA 89.62000
LogP 3.40520
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%