255734-04-4

255734-04-4 structure

Name: KUC-7322
Chemical Name: 2-[4-[2-[[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]-2,5-dimethylphenoxy]acetic acid
CAS Number: 255734-04-4
Molecular Formula: C₂₁H₂₇NO₅
Molecular Weight: 373.44300
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2017-09-27 06:28:12
Modify Date: 2024-01-03 21:11:59
KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.

Name	2-[4-[2-[[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]-2,5-dimethylphenoxy]acetic acid

Description	KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Metabolic Disease
References	[1]. Igawa Y, Schneider T, Yamazaki Y, et al. Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322. Naunyn Schmiedebergs Arch Pharmacol. 2012;385(8):759-767. [2]. Abe Y, Nakano Y, Kanazawa T, Furihata T, Endo T, Kobayashi M. Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men. Clin Pharmacol Drug Dev. 2016;5(3):201-207.