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624-18-0

624-18-0 structure
624-18-0 structure

Name 1,4-Diaminobenzene Dihydrochloride
Synonyms 1,4-Benzenediamine dihydrochloride
Benzene-1,4-diamine dihydrochloride
EINECS 210-834-9
1,4-Benzenediamine, hydrochloride (1:2)
benzene-1,4-diamine,dihydrochloride
Benzol-1,4-diamindihydrochlorid
MFCD00013002
Density 1.15 g/cm3
Boiling Point 267.4ºC at 760 mmHg
Melting Point >200°C
Molecular Formula C6H10Cl2N2
Molecular Weight 181.063
Flash Point 135.9ºC
Exact Mass 180.022110
PSA 52.04000
LogP 3.61740
Water Solubility >=10 g/100 mL at 21 ºC

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ST0350000
CHEMICAL NAME :
p-Phenylenediamine, dihydrochloride
CAS REGISTRY NUMBER :
624-18-0
LAST UPDATED :
199710
DATA ITEMS CITED :
19
MOLECULAR FORMULA :
C6-H8-N2.2Cl-H
MOLECULAR WEIGHT :
181.08
WISWESSER LINE NOTATION :
ZR DZ &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Specific locus test

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
1250 ug/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),103,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,125,1978
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H311-H317-H319-H331-H410
Precautionary Statements P261-P273-P280-P301 + P310-P305 + P351 + P338-P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic
Risk Phrases R23/24/25;R36;R43;R50/53
Safety Phrases S28-S36/37-S45-S60-S61-S28A
RIDADR UN 1673 6.1/PG 3
WGK Germany 3
RTECS ST0350000
Packaging Group III
Hazard Class 6.1
HS Code 29215119

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624-18-0 structure

624-18-0

Literature: Journal of the American Chemical Society, , vol. 45, p. 2351,2354
HS Code 2921519090
Summary 2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%