Benzene-1,4-diammonium chloride

Modify Date: 2024-01-02 12:29:40

Benzene-1,4-diammonium chloride structure	Common Name	Benzene-1,4-diammonium chloride
	CAS Number	624-18-0	Molecular Weight	181.063
	Density	1.15 g/cm3	Boiling Point	267.4ºC at 760 mmHg
	Molecular Formula	C₆H₁₀Cl₂N₂	Melting Point	>200°C
	MSDS	Chinese USA	Flash Point	135.9ºC
	Symbol	GHS06, GHS09	Signal Word	Danger

Name	1,4-Diaminobenzene Dihydrochloride
Synonym	More Synonyms

Density	1.15 g/cm3
Boiling Point	267.4ºC at 760 mmHg
Melting Point	>200°C
Molecular Formula	C₆H₁₀Cl₂N₂
Molecular Weight	181.063
Flash Point	135.9ºC
Exact Mass	180.022110
PSA	52.04000
LogP	3.61740
Water Solubility	>=10 g/100 mL at 21 ºC

Benzene-1,4-diammonium chloride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ST0350000

CHEMICAL NAME :: p-Phenylenediamine, dihydrochloride

CAS REGISTRY NUMBER :: 624-18-0

LAST UPDATED :: 199710

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C6-H8-N2.2Cl-H

MOLECULAR WEIGHT :: 181.08

WISWESSER LINE NOTATION :: ZR DZ &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 147 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 1250 ug/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),103,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,125,1978

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H311-H317-H319-H331-H410
Precautionary Statements	P261-P273-P280-P301 + P310-P305 + P351 + P338-P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic
Risk Phrases	R23/24/25;R36;R43;R50/53
Safety Phrases	S28-S36/37-S45-S60-S61-S28A
RIDADR	UN 1673 6.1/PG 3
WGK Germany	3
RTECS	ST0350000
Packaging Group	III
Hazard Class	6.1
HS Code	29215119

Hydrochloric acid

CAS#:7647-01-0

N-(4-ISOTHIOCYA...

CAS#:35008-62-9

Benzene-1,4-dia...

CAS#:624-18-0

Literature: Journal of the American Chemical Society, , vol. 45, p. 2351,2354

Precursor 2
CAS#:7647-01-0 Hydrochloric acid CAS#:35008-62-9 N-(4-ISOTHIOCYA...
DownStream 10
CAS#:100-22-1 Wurster's blue CAS#:100-25-4 P-DINITROBENZENE CAS#:15165-86-3 h3b*nh2c6h4-4-n... CAS#:17625-83-1 4'-Aminobenzanilide
CAS#:5467-04-9 Benzamide, N,N-... CAS#:119516-83-5 1,4-(2H4)Benzen... CAS#:19201-32-2 N-(2-Aminoethyl... CAS#:18996-77-5 1-N,1-N,4-N,4-N...
CAS#:6976-08-5 2-[4-(diaminome... CAS#:92492-55-2 4-chloro-N-[4-(...

HS Code	2921519090
Summary	2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

Interaction of ceruloplasmin with eosinophil peroxidase as compared to its interplay with myeloperoxidase: Reciprocal effect on enzymatic properties.

Free Radic. Res. 49 , 800-11, (2015)

Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are involved in the development of halogenative stress during inflammation. We previously described a complex between MPO and ceruloplasmin (CP). ...

Development and validation of an LC-MS/MS method for determination of p-phenylenediamine and its metabolites in blood samples.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 997 , 1-6, (2015)

In some developing countries, p-phenylenediamine (PPD) is used in combination with Henna as hair dye or skin decoration. A sensitive LC-MS/MS method was developed and validated for the simultaneous de...

Quantitative risk assessment for skin sensitisation: consideration of a simplified approach for hair dye ingredients.

Regul Toxicol Pharmacol 64(3) , 459-65, (2012)

With the availability of the local lymph node assay, and the ability to evaluate effectively the relative skin sensitizing potency of contact allergens, a model for quantitative-risk-assessment (QRA) ...

1,4-Benzenediamine dihydrochloride

Benzene-1,4-diamine dihydrochloride

EINECS 210-834-9

1,4-Benzenediamine, hydrochloride (1:2)

benzene-1,4-diamine,dihydrochloride

Benzol-1,4-diamindihydrochlorid

MFCD00013002