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609-23-4

609-23-4 structure
609-23-4 structure
  • Name: 2,4,6-Triiodophenol
  • Chemical Name: 2,4,6-Triiodophenol
  • CAS Number: 609-23-4
  • Molecular Formula: C6H3I3O
  • Molecular Weight: 471.801
  • Catalog: Chemical reagent Organic reagent Phenols
  • Create Date: 2018-02-27 08:00:00
  • Modify Date: 2024-01-02 19:20:50
  • 2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2].

Name 2,4,6-Triiodophenol
Synonyms 2,6-Triiodophenol
2,4,6-Triiodophenol
Phenol,4,6-triiodo
2,4,6-Trijodfenol
triiodo-2,4,6 phenol
2,3-DIHYDROXYL QUINOXALINE
Phenol, 2,4,6-triiodo-
Phenol,2,4,6-triiodo
EINECS 210-186-7
2,4,6-Trijodfenol [Czech]
2,4,6-triIPhOH
MFCD00002179
2,4,6-triiodo-phenol
Description 2,4,6-Triiodophenol is an orally active and potent leukotriene B4 (LTB4) synthesis inhibitor. 2,4,6-Triiodophenol can induce mouse blastocysts apoptosis[1][2].
Related Catalog
In Vitro 2,4,6-Triiodophenol (5-50 μM; 0-100 h) impairs the quality of pre-implantation mouse embryos in a dose-dependent manner, inducing decline of both total and trophectoderm cell numbers[2]. 2,4,6-Triiodophenol (5 μM; 85 h) shows increasement of apoptotic cells in mouse pre-implantation embryos[2]. 2,4,6-Triiodophenol (5-50 μM; 100 h) induces oxidative stress in mouse pre-implantation embryos[2]. Apoptosis Analysis[2] Cell Line: Mouse blastocyst cells Concentration: 5 μM Incubation Time: 85 hours Result: Showed signals of activated Caspase-3/7. Immunofluorescence[2] Cell Line: Mouse blastocyst cells Concentration: 5-50 μM Incubation Time: 100 hours Result: Resulted in marked increase of oxygen species (ROS) treated with high dose of 2,4,6-Triiodophenol.
Density 3.1±0.1 g/cm3
Boiling Point 316.3±42.0 °C at 760 mmHg
Melting Point 157-159 °C(lit.)
Molecular Formula C6H3I3O
Molecular Weight 471.801
Flash Point 145.1±27.9 °C
Exact Mass 471.731781
PSA 20.23000
LogP 3.88
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.816

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN2800000
CHEMICAL NAME :
Phenol, 2,4,6-triiodo-
CAS REGISTRY NUMBER :
609-23-4
BEILSTEIN REFERENCE NO. :
2046861
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H3-I3-O
MOLECULAR WEIGHT :
471.79
WISWESSER LINE NOTATION :
QR BI DI FI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 18,642,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03493
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H312 + H332-H315-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS SN2800000
HS Code 2908199090
HS Code 2908199090
Summary HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%