88404-14-2
88404-14-2 structure
- Name: 6,7-Dihydroxycoumarin-4-acetic Acid
- Chemical Name: 6,7-Dihydroxycoumarin-4-acetic Acid
- CAS Number: 88404-14-2
- Molecular Formula: C11H8O6
- Molecular Weight: 236.17800
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Aldose Reductase
- Create Date: 2018-07-02 14:01:39
- Modify Date: 2024-01-06 23:16:21
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6,7-Dihydroxy-4-coumarinylacetic acid is a potent and selective inhibitor of ALR2. 6,7-Dihydroxy-4-coumarinylacetic acid inhibits ALR2, SDH andALR1 with IC50s of 9.6, 288 and 66.3 μM, respectively. 6,7-Dihydroxy-4-coumarinylacetic acid clearly suppresses galactitol accumulation[1].
| Name | 6,7-Dihydroxycoumarin-4-acetic Acid |
|---|---|
| Synonyms | 2-(6,7-dihydroxy-2-oxochromen-4-yl)acetic acid |
| Description | 6,7-Dihydroxy-4-coumarinylacetic acid is a potent and selective inhibitor of ALR2. 6,7-Dihydroxy-4-coumarinylacetic acid inhibits ALR2, SDH andALR1 with IC50s of 9.6, 288 and 66.3 μM, respectively. 6,7-Dihydroxy-4-coumarinylacetic acid clearly suppresses galactitol accumulation[1]. |
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| Related Catalog | |
| References |
| Melting Point | 230ºC |
|---|---|
| Molecular Formula | C11H8O6 |
| Molecular Weight | 236.17800 |
| Exact Mass | 236.03200 |
| PSA | 107.97000 |
| LogP | 0.83130 |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
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88404-14-2 |
| Literature: Journal of the Chemical Society, , vol. 107, p. 1637 |
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88404-14-2 |
| Literature: Annales Pharmaceutiques Francaises, , vol. 7, p. 439 |
