10299-44-2
10299-44-2 structure
- Name: 3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine,3-β-D-ribofuranosyl-
- Chemical Name: 8-azaadenosine
- CAS Number: 10299-44-2
- Molecular Formula: C9H12N6O4
- Molecular Weight: 268.22900
- Catalog: Signaling Pathways Others Others
- Create Date: 2017-07-18 01:04:38
- Modify Date: 2024-01-04 21:53:29
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8-Azaadenosine is a potent ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. 8-Azaadenosine reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells self-renewal in vitro.
| Name | 8-azaadenosine |
|---|---|
| Synonyms |
8-aza-adenosine
8-Aza-adenosin |
| Description | 8-Azaadenosine is a potent ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. 8-Azaadenosine reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells self-renewal in vitro. |
|---|---|
| Related Catalog |
| Density | 2.29 g/cm3 |
|---|---|
| Boiling Point | 702.6ºC at 760 mmHg |
| Molecular Formula | C9H12N6O4 |
| Molecular Weight | 268.22900 |
| Flash Point | 378.7ºC |
| Exact Mass | 268.09200 |
| PSA | 152.43000 |
| Vapour Pressure | 1.01E-20mmHg at 25°C |
| Index of Refraction | 2 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Precursor 0 | |
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| DownStream 1 | |
![3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine,3-[2,3-O-(1-methylethylidene)-b-D-ribofuranosyl]- structure](https://www.chemsrc.com/caspic/080/53458-40-5.png)