352438-80-3

352438-80-3 structure

Name: 3-(4-Isopropylphenyl)-1-methyl-1-(2H3)methylurea
Chemical Name: 1-methyl-3-(4-propan-2-ylphenyl)-1-(trideuteriomethyl)urea
CAS Number: 352438-80-3
Molecular Formula: C₁₂H₁₅D₃N₂O
Molecular Weight: 209.303
Catalog: Research Areas Others
Create Date: 2018-07-16 14:09:11
Modify Date: 2024-01-09 19:29:48
Isoproturon-d3 is the deuterium labeled Isoproturon[1]. Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley[2][3].

Name	1-methyl-3-(4-propan-2-ylphenyl)-1-(trideuteriomethyl)urea
Synonyms	Protugan-d3 Izoturon-d3 Graminon-d3 Harpun-d3 Arelon R-d3 Urea, N-methyl-N-methyl-d-N'-[4-(1-methylethyl)phenyl]- 3-(4-Isopropylphenyl)-1-methyl-1-(H)methylurea Isoproturon-d3 Tolkan-d3 Alon-d3

Description	Isoproturon-d3 is the deuterium labeled Isoproturon[1]. Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley[2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Feng Fan Lu, et al. Isoproturon-Induced Salicylic Acid Confers Arabidopsis Resistance to Isoproturon Phytotoxicity and Degradation in Plants. J Agric Food Chem. 2018 Dec 19;66(50):13073-13083. [3]. Mian Muhammad, et al. Determination of Isoproturon in Environmental Samples Using the QuEChERS Extraction-Spectrofluorimetric Method. Environ Toxicol Chem. 2019 Dec38(12):2614-2620.