35693-18-6

35693-18-6 structure
35693-18-6 structure
  • Name: (β,β-2H2)Tyrosine
  • Chemical Name: dl-4-hydroxyphenylalanine-3,3-d2
  • CAS Number: 35693-18-6
  • Molecular Formula: C9H9D2NO3
  • Molecular Weight: 183.20
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2018-09-14 21:32:59
  • Modify Date: 2024-01-10 15:37:59
  • DL-Tyrosine-d2 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1][2].

Name dl-4-hydroxyphenylalanine-3,3-d2
Synonyms (β,β-H)Tyrosine
Tyrosine-β,β-d
Description DL-Tyrosine-d2 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. ClementeBretti, et al. Some thermodynamic properties of dl-Tyrosine and dl-Tryptophan. Effect of the ionic medium, ionic strength and temperature on the solubility and acid–base properties. Fluid Phase Equilibria.

Density 1.3±0.1 g/cm3
Boiling Point 385.2±32.0 °C at 760 mmHg
Molecular Formula C9H9D2NO3
Molecular Weight 183.20
Flash Point 186.7±25.1 °C
Exact Mass 183.086441
PSA 83.55000
LogP 0.38
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.614
Storage condition -20C