937265-83-3
937265-83-3 structure
- Name: ARRY-380
- Chemical Name: 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine
- CAS Number: 937265-83-3
- Molecular Formula: C29H27N7O4S
- Molecular Weight: 569.634
- Catalog: Biochemical Inhibitor Protein tyrosine kinase
- Create Date: 2018-12-27 19:32:03
- Modify Date: 2024-01-04 18:52:57
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The product is the analog of ARRY-380, ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR
| Name | 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine |
|---|---|
| Synonyms |
HER2-Inhibitor-1
UNII-H32S1659ED CS-0484 cc-595 Arry-380 ARRY-380 (analog ) |
| Description | The product is the analog of ARRY-380, ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C29H27N7O4S |
| Molecular Weight | 569.634 |
| Exact Mass | 569.184509 |
| PSA | 144.92000 |
| LogP | 3.59 |
| Index of Refraction | 1.709 |
| Storage condition | -20℃ |