ARRY-380

Modify Date: 2024-01-04 18:52:57

ARRY-380 Structure
ARRY-380 structure
Common Name ARRY-380
CAS Number 937265-83-3 Molecular Weight 569.634
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C29H27N7O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARRY-380


The product is the analog of ARRY-380, ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR

 Names

Name 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine
Synonym More Synonyms

 ARRY-380 Biological Activity

Description The product is the analog of ARRY-380, ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR
Related Catalog
References

[1]. ErbB-2 inhibitor ARRY-380

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C29H27N7O4S
Molecular Weight 569.634
Exact Mass 569.184509
PSA 144.92000
LogP 3.59
Index of Refraction 1.709
Storage condition -20℃

 Synonyms

HER2-Inhibitor-1
UNII-H32S1659ED
CS-0484
cc-595
Arry-380
ARRY-380 (analog )
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Price: $180/10mM*1mLinDMSO

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