ARRY 520 trifluoroacetate

Modify Date: 2024-01-07 18:09:06

ARRY 520 trifluoroacetate Structure
ARRY 520 trifluoroacetate structure
Common Name ARRY 520 trifluoroacetate
CAS Number 1781834-99-8 Molecular Weight 534.499
Density N/A Boiling Point N/A
Molecular Formula C22H23F5N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARRY 520 trifluoroacetate


Filanesib, also known as ARRY-520, is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Because KSP is not involved in postmitotic processes, such as neuronal transport, this agent does not cause the peripheral neuropathy that is often associated with tubulin-targeting agents.

 Names

Name ARRY-520
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H23F5N4O4S
Molecular Weight 534.499
Exact Mass 534.135986

 Synonyms

Acetic acid, 2,2,2-trifluoro-, compd. with (2S)-2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide (1:1)
(2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide trifluoroacetate (1:1)
ARRY-520
Top Suppliers:I want be here



Get all suppliers and price by the below link:

ARRY 520 trifluoroacetate suppliers

ARRY 520 trifluoroacetate price