1097917-15-1
- Name: ASP3026
- Chemical Name: 2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
- CAS Number: 1097917-15-1
- Molecular Formula: C29H40N8O3S
- Molecular Weight: 580.745
- Catalog: Biochemical Inhibitor Protein tyrosine kinase
- Create Date: 2016-09-18 10:15:15
- Modify Date: 2024-01-02 12:26:26
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ASP3026 is a novel and selective inhibitor for ALK (anaplastic lymphoma kinase) with IC50 of 3.5 nM.
| Name | 2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine |
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| Synonyms |
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
cc-325 QCR-144 N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N'-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine ASP 3026 N-[2-(isopropylsulfonyl)phenyl]-N'-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-1,3,5-triazine-2,4-diamine 1,3,5-Triazine-2,4-diamine, N-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N-[2-[(1-methylethyl)sulfonyl]phenyl]- CS-0787 UNII-HP4L6MXF10 N-[2-(Isopropylsulfonyl)phenyl]-N'-{2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl}-1,3,5-triazine-2,4-diamine ASP3026 |
| Description | ASP3026 is a novel and selective inhibitor for ALK (anaplastic lymphoma kinase) with IC50 of 3.5 nM. |
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| Related Catalog | |
| References |
[1]. Sadao Kuromitsu, et al. AACR 102nd Annual Meeting, 2011. |
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 794.3±70.0 °C at 760 mmHg |
| Molecular Formula | C29H40N8O3S |
| Molecular Weight | 580.745 |
| Flash Point | 434.2±35.7 °C |
| Exact Mass | 580.294434 |
| PSA | 127.43000 |
| LogP | 1.01 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.620 |
| Storage condition | -20°C |
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| Literature: Astellas Pharma Inc.; OBITSU, Kazuyoshi; AKIBA, Takahiro; KOBAYASHI, Koji; HIRASAWA, Shun; KONDOH, Yutaka; TAKEGUCHI, Kazuhiro; TAKAHAMA, Yuji; ORII, Ryoki Patent: EP2669281 A1, 2013 ; Location in patent: Paragraph 0059 ; |
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| Precursor 9 | |
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| DownStream 0 | |