397290-30-1

397290-30-1 structure

Name: ue1654
Chemical Name: N-[7-(Methylsulfanyl)[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl]- 2,2-diphenylacetamide
CAS Number: 397290-30-1
Molecular Formula: C₂₃H₁₇N₃OS₃
Molecular Weight: 447.59600
Create Date: 2016-04-03 12:12:19
Modify Date: 2024-01-02 19:29:38
Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].

Name	N-[7-(Methylsulfanyl)[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl]- 2,2-diphenylacetamide

Description	Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Blättermann S, et al. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
RIDADR	NONH for all modes of transport