ue1654

Modify Date: 2024-01-02 19:29:38

ue1654 Structure
ue1654 structure
Common Name ue1654
CAS Number 397290-30-1 Molecular Weight 447.59600
Density N/A Boiling Point N/A
Molecular Formula C23H17N3OS3 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of ue1654


Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].

 Names

Name N-[7-(Methylsulfanyl)[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl]- 2,2-diphenylacetamide

 ue1654 Biological Activity

Description Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ[1].
Related Catalog
References

[1]. Blättermann S, et al. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.

 Chemical & Physical Properties

Molecular Formula C23H17N3OS3
Molecular Weight 447.59600
Exact Mass 447.05300
PSA 140.15000
LogP 7.04800

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport
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