61-32-5

61-32-5 structure

Name: Meticillin
Chemical Name: methicillin
CAS Number: 61-32-5
Molecular Formula: C₁₇H₂₀N₂O₆S
Molecular Weight: 380.41600
Catalog: Organic raw materials Carboxylic compounds and derivatives Carboxylic esters and their derivatives
Create Date: 2016-01-07 04:51:50
Modify Date: 2024-01-15 20:04:58
Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis[1].

Name	methicillin
Synonyms	Meticillin meticillin 6β-(2,6-dimethoxy-benzoylamino)-penicillanic acid METICILLIN 6-(2,6-dimethoxybenzamido)penicillinic acid (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Methicillin methycillin

Description	Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Methicillin (20 μg/mL, 24 h) results in a rapid decrease in CFU of S. aureus[2].
In Vivo	Methicillin (Intramuscular administration, 40 mg/kg every 6 h, 5 days), in S. aureus.-infected rabbits[2].
References	[1]. Sharon S. Castle. Methicillin. xPharm: The Comprehensive Pharmacology Reference 2007, Pages 1-4. [2]. Jaime Carrizosa, et al. Treatment of Experimental Staphylococcus aureus Endocarditis: Comparison of Cephalothin, Cefazolin, and Methicillin. Antimicrob Agents Chemother. 1978 Jan; 13(1): 74–77.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
RIDADR	NONH for all modes of transport
RTECS	XH8930000

Precursor 0
DownStream 1
51579-21-6