603-41-8

603-41-8 structure

Name: Desacetyl Bisacodyl
Chemical Name: 4-[(4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol
CAS Number: 603-41-8
Molecular Formula: C₁₈H₁₅NO₂
Molecular Weight: 277.32
Catalog: Research Areas Metabolic Disease
Create Date: 2018-04-26 08:00:00
Modify Date: 2024-01-09 23:27:34
Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].

Name	4-[(4-hydroxyphenyl)-pyridin-2-ylmethyl]phenol
Synonyms	4,4'-pyridin-2-ylmethanediyl-bis-phenol EINECS 210-039-7 Deacetylbisocodyl DDPM La-96 deacetylbisacodyl Dihydroxydiphenyl-pyridyl methane

Description	Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Fujita T, et, al. Desacetyl bisacodyl-induced epithelial Cl(-) secretion in rat colon and rectum. Biomed Res. 2016;37(1):13-20.

TOXIC EFFECTS :: Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NAIZAM Nara Igaku Zasshi. Journal of the Nara Medical Association. (Nara Igakkai, c/o Narakenritsu Ika Daigaku, Shijo-cho, Kashihara, Nara-ken, Japan) V.1- 1950- Volume(issue)/page/year: 28,258,1977

RIDADR	NONH for all modes of transport