Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 6-Maleimidocapronic acid
Price: ￥138.0/5g ￥498.0/25g ￥248.0/10g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: 6-Maleimidocapronic acid
Price: ￥Inquiry/10g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Lihua Yang

DC Chemicals Limited
China
Product Name: 6-Maleimidocaproic acid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6-Maleimidocaproic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

55750-53-3

55750-53-3 structure

55750-53-3 structure

Name: 6-Maleimidocapronic acid
Chemical Name: 6-Maleimidocaproic Acid
CAS Number: 55750-53-3
Molecular Formula: C₁₀H₁₃NO₄
Molecular Weight: 211.214
Catalog: Organic raw materials Carboxylic compounds and derivatives Acyclic carboxylic acid
Create Date: 2018-06-13 20:49:35
Modify Date: 2024-01-03 21:27:12
6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	6-Maleimidocaproic Acid
Synonyms	6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid MFCD00043140 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo- 6-(2,5-dioxopyrrol-1-yl)hexanoic acid

Description	6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.3±0.1 g/cm3
Boiling Point	407.3±28.0 °C at 760 mmHg
Melting Point	86-91ºC
Molecular Formula	C₁₀H₁₃NO₄
Molecular Weight	211.214
Flash Point	200.1±24.0 °C
Exact Mass	211.084457
PSA	74.68000
LogP	0.71
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.537
Storage condition	2-8°C

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2925190090

57079-14-8 structure

57079-14-8

~71%

55750-53-3 structure

55750-53-3

Literature: Dalton Transactions, , # 24 p. 3886 - 3897

108-31-6 structure

108-31-6

60-32-2 structure

60-32-2

~74%

55750-53-3 structure

55750-53-3

Literature: Journal of Medicinal Chemistry, , vol. 56, # 24 p. 9955 - 9968

108-31-6 structure

108-31-6

7440-44-0 structure

7440-44-0

60-32-2 structure

60-32-2

~30%

55750-53-3 structure

55750-53-3

Literature: EP665020 A3, ;

108-31-6 structure

108-31-6

~%

55750-53-3 structure

55750-53-3

57079-14-8 structure

57079-14-8

Literature: US8241655 B2, ;

60-32-2 structure

60-32-2

~%

55750-53-3 structure

55750-53-3

Literature: Dalton Transactions, , # 24 p. 3886 - 3897

Precursor 4
57079-14-8 108-31-6 60-32-2 7440-44-0
DownStream 4
55750-63-5 57-13-6 157503-18-9 82333-93-5

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%