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3106-85-2

3106-85-2 structure
3106-85-2 structure
  • Name: Spaglumic Acid
  • Chemical Name: n-acetyl-asp-glu
  • CAS Number: 3106-85-2
  • Molecular Formula: C11H16N2O8
  • Molecular Weight: 304.253
  • Catalog: Biochemical Peptide
  • Create Date: 2018-02-14 08:00:00
  • Modify Date: 2024-01-03 00:12:34
  • Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.

Name n-acetyl-asp-glu
Synonyms N-Acetyl-L-aspartyl-L-glutamic acid
N-acetyl-1-aspartylglutamic acid
NAAGA
AC-ASP-GLU
SPAGLUMIC ACID
N-(N-Acetyl-L-a-aspartyl)-L-glutamic Acid
N-acetyl-L-aspartyl-L-glutamate
N-Acetyl-L-α-aspartyl-L-glutamic acid
isospaglumic acid
L-Glutamic acid, N-acetyl-L-α-aspartyl-
AC-ASP-GLU H2O
AC-ASP-GLU-OH
MFCD00076652
Tacrine hydrochloride
N-acetyl-aspartatylglutamate
N-(N-Acetyl-L-α-aspartyl)-L-glutamic acid
glutamic acid, N-acetylaspartyl-
ACETYL-D-E
Naaxia
NAAG
N-Acetylaspartylglutamic acid
NAAG Spaglumic acid
Description Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Isospaglumic acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of NAAG and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1].
References

[1]. Coyle JT. The nagging question of the function of N-acetylaspartylglutamate. Neurobiol Dis. 1997;4(3-4):231-8.

Density 1.5±0.1 g/cm3
Boiling Point 769.5±60.0 °C at 760 mmHg
Molecular Formula C11H16N2O8
Molecular Weight 304.253
Flash Point 419.1±32.9 °C
Exact Mass 304.090668
PSA 170.10000
LogP -1.96
Vapour Pressure 0.0±5.7 mmHg at 25°C
Index of Refraction 1.540
Storage condition −20°C
Water Solubility H2O: 50 mg/mL
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2924199090
Precursor  1

DownStream  2

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%