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341-70-8

341-70-8 structure
341-70-8 structure
  • Name: diethazine hydrochloride
  • Chemical Name: N,N-diethyl-2-phenothiazin-10-ylethanamine,hydrochloride
  • CAS Number: 341-70-8
  • Molecular Formula: C18H23ClN2S
  • Molecular Weight: 334.90700
  • Create Date: 2016-05-26 12:10:29
  • Modify Date: 2024-01-09 18:21:29

Name N,N-diethyl-2-phenothiazin-10-ylethanamine,hydrochloride
Synonyms diethyl-(2-phenothiazin-10-yl-ethyl)-amine,monohydrochloride
Deparkin
diethyl-(2-phenothiazin-10-yl-ethyl)-amine,hydrochloride
Antipar
Diethazine hydrochloride
Diethazinhydrochlorid
Dinezin
Diparcol
Aparkazin
Thiantan
10-[2-(diethylamino)ethyl]phenothiazine hydrochloride
Thiontan
Dinezine
Latibon
Boiling Point 422.2ºC at 760 mmHg
Molecular Formula C18H23ClN2S
Molecular Weight 334.90700
Flash Point 209.1ºC
Exact Mass 334.12700
PSA 31.78000
LogP 5.49810

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO4375000
CHEMICAL NAME :
Phenothiazine, 10-(2-(diethylamino)ethyl)-, monohydrochloride
CAS REGISTRY NUMBER :
341-70-8
LAST UPDATED :
199706
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C18-H22-N2-S .Cl-H
MOLECULAR WEIGHT :
334.94
WISWESSER LINE NOTATION :
T C666 BN ISJ B2N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2500 ug/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - parasympatholytic

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
20 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981
HS Code 2934300000
HS Code 2934300000
Summary 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%