169751-10-4

169751-10-4 structure

Name: Sulfo-SPDP-C6-NHS sodium
Chemical Name: sodium,2,5-dioxo-1-[6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexanoyloxy]pyrrolidine-3-sulfonate
CAS Number: 169751-10-4
Molecular Formula: C₁₈H₂₂N₃NaO₈S₃
Molecular Weight: 527.56700
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2017-05-11 04:48:58
Modify Date: 2024-01-11 16:38:24
Sulfo-SPDP-C6-NHS sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	sodium,2,5-dioxo-1-[6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexanoyloxy]pyrrolidine-3-sulfonate
Synonyms	sodium 2,5-dioxo-1-[6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexanoyloxy]pyrrolidine-3-sulfonate Sulfo-LC-SPDP 2,5-Dioxo-1-[[1-oxo-6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]oxy]-3-pyrrolidinesulfonic Acid Monosodium Salt Sulfo-N-succinimidyl 6-[3-(2-Pyridyldithio)propionamido] Hexanoate,Sodium Salt

Description	Sulfo-SPDP-C6-NHS sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.