1141-41-9

1141-41-9 structure

Name: IDT307
Chemical Name: N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline,iodide
CAS Number: 1141-41-9
Molecular Formula: C₁₄H₁₇IN₂
Molecular Weight: 340.20300
Catalog: Research Areas Others
Create Date: 2016-04-22 18:42:35
Modify Date: 2024-01-08 12:57:23
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].

Name	N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline,iodide

Description	IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1]. IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1].
References	[1]. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018.