IDT307

Modify Date: 2024-01-08 12:57:23

IDT307 Structure
IDT307 structure
Common Name IDT307
CAS Number 1141-41-9 Molecular Weight 340.20300
Density N/A Boiling Point N/A
Molecular Formula C14H17IN2 Melting Point 180-182 °C
MSDS USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of IDT307


IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].

 Names

Name N,N-dimethyl-4-(1-methylpyridin-1-ium-4-yl)aniline,iodide

 IDT307 Biological Activity

Description IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+)[1].
Related Catalog
In Vitro IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1]. IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1].
References

[1]. Tao Hu, et al. Molecular mechanisms of organic cation and anion transport at the blood‐CSF barrier. 01 April 2018.

 Chemical & Physical Properties

Melting Point 180-182 °C
Molecular Formula C14H17IN2
Molecular Weight 340.20300
Exact Mass 340.04400
PSA 7.12000
Storage condition 20°C

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300
Precautionary Statements P264-P301 + P310
Hazard Codes T
RIDADR UN 2811 6.1 / PGIII
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