21416-68-2

21416-68-2 structure
21416-68-2 structure
  • Name: ICRF-196
  • Chemical Name: 4-[3-(3,5-dioxopiperazin-1-yl)butan-2-yl]piperazine-2,6-dione
  • CAS Number: 21416-68-2
  • Molecular Formula: C12H18N4O4
  • Molecular Weight: 282.30
  • Create Date: 2017-06-04 23:42:14
  • Modify Date: 2024-01-21 17:48:32
  • ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is an TopoII inhibitor. ICRF-196 can be used for the research of cancer[1].

Name 4-[3-(3,5-dioxopiperazin-1-yl)butan-2-yl]piperazine-2,6-dione
Synonyms C12H18N4O4
Icrf 193
Description ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is an TopoII inhibitor. ICRF-196 can be used for the research of cancer[1].
Related Catalog
References

[1]. Snapka RM,et al. Inhibition of topoisomerase II by ICRF-193, the meso isomer of 2,3-bis(2,6-dioxopiperazin-4-yl)butane. Critical dependence on 2,3-butanediyl linker absolute configuration. Biochem Pharmacol. 1996;52(4):543-549.  

Density 1.308g/cm3
Boiling Point 526.7ºC at 760mmHg
Molecular Formula C12H18N4O4
Molecular Weight 282.30
Flash Point 272.4ºC
Exact Mass 282.13300
PSA 98.82000
Vapour Pressure 3.48E-11mmHg at 25°C
Index of Refraction 1.539
HS Code 2933599090
HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%