2159-18-4

2159-18-4 structure

Name: 1-(2,2,3,3,4,4,5,5,6,6,6-2H11)Hexanol
Chemical Name: n-hexyl-2,2,3,3,4,4,5,5,6,6,6-d11 alcohol
CAS Number: 2159-18-4
Molecular Formula: C₆H₃D₁₁O
Molecular Weight: 113.243
Catalog: Research Areas Others
Create Date: 2018-07-20 22:58:57
Modify Date: 2024-01-15 00:15:44
1-Hexanol-d11 is the deuterium labeled 1-Hexanol[1]. 1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[2]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[3].

Name	n-hexyl-2,2,3,3,4,4,5,5,6,6,6-d11 alcohol
Synonyms	Nonafluorvaleraldehyd-hydrat 1H-Perfluoropentane-1,1-diol 1-Hexan-2,2,3,3,4,4,5,5,6,6,6-d-ol nonafluoropentanal hydrate (2,2,3,3,4,4,5,5,6,6,6-H)Hexan-1-ol 1H-Nonafluor-pentan-1,1-diol 2,2,3,3,4,4,5,5,5-Nonafluoropentane-1,1-diol 2,2,3,3,4,4,5,5,6,6,6-Undecadeutero-hexylalkohol 2,2,3,3,4,4,5,5,6,6,6-undecadeuterio-hexan-1-ol 2,2,3,3,4,4,5,5,5-Nonafluoro-1,1-pentanediol 1-(2,2,3,3,4,4,5,5,6,6,6-H)Hexanol 1H-nonafluoro-pentane-1,1-diol

Description	1-Hexanol-d11 is the deuterium labeled 1-Hexanol[1]. 1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[2]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Cuong V Nguyen, et al. Surface potential of 1-hexanol solution: comparison with methyl isobutyl carbinol. J Phys Chem B. 2013 Jun 27;117(25):7615-20. [3]. M Canton, et al. The nature of uncoupling by n-hexane, 1-hexanethiol and 1-hexanol in rat liver mitochondria. Biochim Biophys Acta. 1996 May 201274(1-2):39-47.