Top Suppliers:I want be here


506-17-2

506-17-2 structure
506-17-2 structure
  • Name: cis-Vaccenic acid
  • Chemical Name: cis-vaccenic acid
  • CAS Number: 506-17-2
  • Molecular Formula: C18H34O2
  • Molecular Weight: 282.461
  • Catalog: Chemical reagent Organic reagent fatty acid
  • Create Date: 2018-05-25 08:00:00
  • Modify Date: 2024-01-07 12:05:19
  • cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate[1], acts a potential fetal hemoglobin inducer[2].

Name cis-vaccenic acid
Synonyms (Z)-11-octadecenoic acid
cis-Vaccenic acid
11-Octadecenoic acid, (Z)-
11-cis-Octadecenoic acid
cis-11-Octadecenoic acid
MFCD00063187
11(Z)-Octadecenoic acid
11-Octadecenoic acid, (11Z)-
(11Z)-11-Octadecenoic acid
asclepic acid
Vaccenic acid
11Z-Octadecenoic acid
(11Z)-Octadec-11-enoic acid
(Z)-vaccenic acid
cis-11-Vaccenic acid
Description cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate[1], acts a potential fetal hemoglobin inducer[2].
Related Catalog
In Vitro cis-Vaccenic acid (CVA) (50 μM, 70 μM and 100 μM) induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells[2]. cis-Vaccenic acid (50 μM) also increased the percentage of benzidine positive JK-1 cell[2]. Cell Differentiation Assay[2] Cell Line: K562 cells Concentration: 50 μM, 70 μM and 100 μM Incubation Time: 48 and 120 hours Result: Induced differentiation appeared to be concentration dependent in K562 cells with 50 μM CVA being the most effective concentration with more than 20% of the K562 cells showing positive for Benzidine stain after 48 h of incubation with CVA.
References

[1]. H Hirotani, et al. Inactivation of T5 phage by cis-vaccenic acid, an antivirus substance from Rhodopseudomonas capsulata, and by unsaturated fatty acids and related alcohols. FEMS Microbiol Lett. 1991 Jan 1;61(1):13-7.

[2]. Idowu A Aimola, et al. Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. Eur J Pharmacol. 2016 Apr 5;776:9-18.

Density 0.9±0.1 g/cm3
Boiling Point 398.2±11.0 °C at 760 mmHg
Melting Point 14-15ºC(lit.)
Molecular Formula C18H34O2
Molecular Weight 282.461
Flash Point 295.0±14.4 °C
Exact Mass 282.255890
PSA 37.30000
LogP 7.70
Appearance oil
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.467
Storage condition −20°C

Section 1. Chemical Product and Company Identification
cis-Vaccenic Acid, synthetic
Common Name/
Trade Name
cis-Vaccenic Acid, synthetic

Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
Eye Contact
15 minutes. Get medical attention if irritation occurs.
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Skin Contact
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Not available.
Serious Inhalation
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Not available.
Serious Ingestion

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
CLOSED CUP: 230°C (446°F).
Flash Points
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2).
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat.
Various Substances
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Risks of explosion of the product in presence of static discharge: Not available.
Presence of Various
Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Not available.
Special Remarks on
Fire Hazards
Not available.
Special Remarks on
Explosion Hazards

Section 6. Accidental Release Measures
Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Small Spill
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by
Large Spill
spreading water on the contaminated surface and allow to evacuate through the sanitary system.
cis-Vaccenic Acid, synthetic

Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
Precautions
breathe gas/fumes/ vapor/spray. Keep away from incompatibles such as oxidizing agents, alkalis.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 0°C (32°F).
Storage
Freeze. Sensitive to light. Store in light-resistant containers.

Section 8. Exposure Controls/Personal Protection
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
Engineering Controls
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
Personal ProtectionSafety glasses. Lab coat. Gloves (impervious).
Personal Protection in Case Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
of a Large Spill
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Liquid.Not available.
Physical state andO dor
appearance
Not available.
Taste
282.47 g/mole
Molecular Weight
Not available.
Color
Not available.
pH (1% soln/water)
158°C (316.4°F) - 163 C. at 0.4 mm Hg
Boiling Point
14°C (57.2°F) -15 C.
Melting Point
Not available.
Critical Temperature
0.88 - 0.89 (Water = 1)
Specific Gravity
Not available.
Vapor Pressure
Not available.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
Not available.
Dispersion Properties
Not available.
Solubility

Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Conditions of Instability Excess heat, incompatible materials
Incompatibility with various Reactive with oxidizing agents, alkalis.
substances
Not available.
Corrosivity
cis-Vaccenic Acid, synthetic
Sensitive to light.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
Will not occur.
Polymerization

Section 11. Toxicological Information
Absorbed through skin. Eye contact. Ingestion.
Routes of Entry
LD50: Not available.
Toxicity to Animals
LC50: Not available.
Chronic Effects on Humans Not available.
Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Humans
Not available.
Special Remarks on
Toxicity to Animals
Not available.
Special Remarks on
Chronic Effects on Humans
Special Remarks on otherAcute Potential Health Effects:
Toxic Effects on HumansSkin: Can cause mild to moderate skin irritation.
Eyes: Can cause mild eye irritation.
Inhalation: Inhalation of mist or vapor may cause respiratory tract irritation.
Ingestion: Expected to be a low hazard.

Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
The product itself and its products of degradation are not toxic.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation

Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control
Waste Disposal
regulations.

Section 14. Transport Information
Not a DOT controlled material (United States).
DO T Cl assi fi cati on
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
cis-Vaccenic Acid, synthetic
DO T (Pi ctograms)

Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
California prop. 65: This product contains the following ingredients for which the State of California has found to
California
cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsEINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance List (NDSL).
China: Not listed on National Inventory.
Japan: Listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Not listed on National Inventory (PICCS).
Australia: Not listed on AICS.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
This product is not classified according Not applicable.
DSCL (EEC)
to the EU regulations.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
1
Specific hazard
Personal Protection
B
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG(Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves (impervious).
cis-Vaccenic Acid, synthetic
Lab coat.
Not applicable.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2916190090
HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%