Name | (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-prop en-1-one |
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Synonyms |
Helichrysetin
4',6'-dihydroxy-2',4-dimethoxychalcone 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)- (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)- 6'-O-methylisosalipurpol |
Description | Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells[1][2]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 532.0±50.0 °C at 760 mmHg |
Molecular Formula | C16H14O5 |
Molecular Weight | 286.279 |
Flash Point | 201.0±23.6 °C |
Exact Mass | 286.084137 |
PSA | 86.99000 |
LogP | 3.08 |
Vapour Pressure | 0.0±1.5 mmHg at 25°C |
Index of Refraction | 1.684 |
Hazard Codes | Xi |
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HS Code | 2914509090 |
~53% 62014-87-3 |
Literature: Aponte, Jose C.; Castillo, Denis; Estevez, Yannick; Gonzalez, German; Arevalo, Jorge; Hammond, Gerald B.; Sauvain, Michel Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 100 - 103 |
~74% 62014-87-3 |
Literature: Vogel, Susanne; Ohmayer, Susanne; Brunner, Gabi; Heilmann, Joerg Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 8 p. 4286 - 4293 |
~% 62014-87-3 |
Literature: Zemplen et al. Chemische Berichte, 1944 , vol. 77/79, p. 446,449 |
Precursor 2 | |
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DownStream 2 | |
HS Code | 2914509090 |
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Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |