629-13-0
629-13-0 structure
- Name: Azide-C2-Azide
- Chemical Name: 1,2-Diazidoethane
- CAS Number: 629-13-0
- Molecular Formula: C2H4N6
- Molecular Weight: 112.09300
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2017-05-15 22:36:14
- Modify Date: 2024-01-09 19:35:43
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Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | 1,2-Diazidoethane |
|---|---|
| Synonyms |
Aethylendiazid
Ethane,1,2-diazido 1,2-Diazido-aethan 1,2-diazido-ethane 1.2-Diazo-aethan Aethylenazid |
| Description | Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Molecular Formula | C2H4N6 |
|---|---|
| Molecular Weight | 112.09300 |
| Exact Mass | 112.05000 |
| PSA | 99.50000 |
| LogP | 0.51252 |
|
~72%
629-13-0 |
| Literature: Betzler, Franziska M.; Klapoetke, Thomas M.; Sproll, Stefan M. European Journal of Organic Chemistry, 2013 , # 3 p. 509 - 514 |
|
~73%
629-13-0 |
| Literature: Vereshchagin, L. I.; Tikhonova, L. G.; Maksikova, A. V.; Serebryakova, E. S.; Proidakov, A. G.; Filippova, T. M. Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 4 p. 641 - 648 Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 4 p. 730 - 738 |
