1222810-74-3
1222810-74-3 structure
- Name: VU591
- Chemical Name: 6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole
- CAS Number: 1222810-74-3
- Molecular Formula: C16H12N6O5
- Molecular Weight: 368.30
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2016-06-10 12:38:04
- Modify Date: 2024-01-08 12:04:20
-
VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1].
| Name | 6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole |
|---|---|
| Synonyms |
2,2 inverted exclamation marka-(oxydimethanediyl)bis(5-nitro-1H-benzimidazole)
ML112 2,2 inverted exclamation marka-(oxydimethanediyl)bis(6-nitro-1H-benzimidazole) 5-nitro-2-{[(6-nitro-1H-benzimidazol-2-yl)methoxy]methyl}-1H-benzimidazole VU591 |
| Description | VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.24 μM (ROMK)[1]. |
| References |
| Molecular Formula | C16H12N6O5 |
|---|---|
| Molecular Weight | 368.30 |
| Exact Mass | 368.08700 |
| PSA | 158.23000 |
| LogP | 4.01880 |
| RIDADR | NONH for all modes of transport |
|---|