VU591

Modify Date: 2024-01-08 12:04:20

VU591 Structure
VU591 structure
Common Name VU591
CAS Number 1222810-74-3 Molecular Weight 368.30
Density N/A Boiling Point N/A
Molecular Formula C16H12N6O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of VU591


VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1].

 Names

Name 6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole
Synonym More Synonyms

 VU591 Biological Activity

Description VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1].
Related Catalog
Target

IC50: 0.24 μM (ROMK)[1].

References

[1]. Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50.

 Chemical & Physical Properties

Molecular Formula C16H12N6O5
Molecular Weight 368.30
Exact Mass 368.08700
PSA 158.23000
LogP 4.01880

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

2,2 inverted exclamation marka-(oxydimethanediyl)bis(5-nitro-1H-benzimidazole)
ML112
2,2 inverted exclamation marka-(oxydimethanediyl)bis(6-nitro-1H-benzimidazole)
5-nitro-2-{[(6-nitro-1H-benzimidazol-2-yl)methoxy]methyl}-1H-benzimidazole
VU591
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Price: ¥990/10 mM * 1 mL in DMSO

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