870480-56-1

870480-56-1 structure
870480-56-1 structure
  • Name: Bis-5,5-nortrachelogenin
  • Chemical Name: Bis-5,5-nortrachelogenin
  • CAS Number: 870480-56-1
  • Molecular Formula: C40H42O14
  • Molecular Weight: 746.75
  • Catalog: Natural product Lignans
  • Create Date: 2017-10-30 08:29:20
  • Modify Date: 2024-04-02 14:53:28
  • Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM[1].

Name Bis-5,5-nortrachelogenin
Synonyms 2(3H)-Furanone, 4,4'-[(6,6'-dihydroxy-5,5'-dimethoxy[1,1'-biphenyl]-3,3'-diyl)bis(methylene)]bis[dihydro-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3S,4S,3'S,4'S)-
(3S,4S,3'S,4'S)-4,4'-[(6,6'-Dihydroxy-5,5'-dimethoxy-3,3'-biphenyldiyl)bis(methylene)]bis[3-hydroxy-3-(4-hydroxy-3-methoxybenzyl)dihydro-2(3H)-furanone]
Description Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM[1].
Related Catalog
References

[1]. Wang LY, et al. Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities. Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51.  

Density 1.4±0.1 g/cm3
Boiling Point 930.9±60.0 °C at 760 mmHg
Molecular Formula C40H42O14
Molecular Weight 746.75
Flash Point 285.1±26.4 °C
Exact Mass 746.257446
PSA 210.90000
LogP 0.48
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.659
Hazard Codes Xi