Name | mabuterol |
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Synonyms |
PB 868Cl
1-(4-Amino-3-chloro-5-(trifluoromethyl)phenyl)-2-(tert-butylamino)ethanol 1-[4-azanyl-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol Ambuterol Benzenemethanol,4-amino-3-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-(9CI) |
Description | Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2]. |
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Related Catalog | |
Target |
Beta-2 adrenergic receptor |
References |
Density | 1.278g/cm3 |
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Boiling Point | 375.9ºC at 760mmHg |
Melting Point | 85-87ºC |
Molecular Formula | C13H18ClF3N2O |
Molecular Weight | 310.74 |
Flash Point | 181.1ºC |
Exact Mass | 310.10600 |
PSA | 58.28000 |
LogP | 4.33460 |
Index of Refraction | 1.516 |
Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
HS Code | 2922199090 |
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HS Code | 2922199090 |
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Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |