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  • DC Chemicals Limited
  • China
  • Product Name: Mabuterol
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

56341-08-3

56341-08-3 structure
56341-08-3 structure
  • Name: Mabuterol
  • Chemical Name: mabuterol
  • CAS Number: 56341-08-3
  • Molecular Formula: C13H18ClF3N2O
  • Molecular Weight: 310.74
  • Catalog: API Respiratory medication Asthma
  • Create Date: 2018-07-11 00:17:37
  • Modify Date: 2024-01-02 11:35:52
  • Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2].

Name mabuterol
Synonyms PB 868Cl
1-(4-Amino-3-chloro-5-(trifluoromethyl)phenyl)-2-(tert-butylamino)ethanol
1-[4-azanyl-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol
Ambuterol
Benzenemethanol,4-amino-3-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-(9CI)
Description Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2].
Related Catalog
Target

Beta-2 adrenergic receptor

References

[1]. Yamamoto I, et al. Enzyme immunoassay for mabuterol, a selective beta 2-adrenergic stimulant in the trachea. J Immunoassay. 1985;6(3):261-76.  

[2]. Yaru Gu, et al. Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca2+]i and mitochondrial fission/fusion. Interactions, 2019, 307: 63-72.

Density 1.278g/cm3
Boiling Point 375.9ºC at 760mmHg
Melting Point 85-87ºC
Molecular Formula C13H18ClF3N2O
Molecular Weight 310.74
Flash Point 181.1ºC
Exact Mass 310.10600
PSA 58.28000
LogP 4.33460
Index of Refraction 1.516
Storage condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere
HS Code 2922199090
HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%