229021-64-1

229021-64-1 structure
229021-64-1 structure
  • Name: Arachidonylcyclopropylamide
  • Chemical Name: Arachidonylcyclopropylamide
  • CAS Number: 229021-64-1
  • Molecular Formula: C23H37NO
  • Molecular Weight: 343.546
  • Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
  • Create Date: 2018-06-22 18:10:06
  • Modify Date: 2024-01-06 06:02:16
  • Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC50=2 nM)[1].

Name Arachidonylcyclopropylamide
Synonyms N-cyclopropylicosa-5,8,11,14-tetraenamide
Arachidonylcyclopropylamide
(5Z,8Z,11Z,14Z)-N-Cyclopropylicosa-5,8,11,14-tetraenamide
5,8,11,14-Eicosatetraenamide, N-cyclopropyl-, (5Z,8Z,11Z,14Z)-
(5Z,8Z,11Z,14Z)-N-Cyclopropyl-5,8,11,14-icosatetraenamide
Description Arachidonylcyclopropylamide (ACPA) is a potent and selective CB1 receptors agonist. Arachidonylcyclopropylamide inhibits forskolin-stimulated cAMP production in CHO cells transfected with human cannabinoid CB1 receptors (IC50=2 nM)[1].
Related Catalog
In Vitro Arachidonylcyclopropylamide induces a dose-dependent increase in BV-2 cell migration (EC50=2.2 nM)[2].
References

[1]. Franklin A, et al. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. Eur J Pharmacol. 2003;474(2-3):195-198.

Density 0.9±0.1 g/cm3
Boiling Point 502.4±50.0 °C at 760 mmHg
Molecular Formula C23H37NO
Molecular Weight 343.546
Flash Point 311.3±15.1 °C
Exact Mass 343.287506
PSA 29.10000
LogP 6.61
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.513
WGK Germany 3