- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 1,1'-Diheptyl-4,4'-bipyridinium dibromide
- Price: ￥486.0/100mg
- Purity: 95.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1,1'-di-n-heptyl-4,4'-bipyridinium dibromide
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
6159-05-3
6159-05-3 structure
- Name: 1,1'-Diheptyl-4,4'-bipyridinium dibromide
- Chemical Name: 1-heptyl-4-(1-heptylpyridin-1-ium-4-yl)pyridin-1-ium,dibromide
- CAS Number: 6159-05-3
- Molecular Formula: C24H38Br2N2
- Molecular Weight: 514.380
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
- Create Date: 2018-12-09 14:40:32
- Modify Date: 2024-01-02 16:26:40
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DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.
| Name | 1-heptyl-4-(1-heptylpyridin-1-ium-4-yl)pyridin-1-ium,dibromide |
|---|---|
| Synonyms |
1,1'-Diheptyl-4,4'-bipyridinium dibromide
N,N'-diheptyl-4,4bipyridinium dibromide N,N′-diheptyl-4,4′-bipyridinium dibromide MFCD00011997 heptylviologen bromide EINECS 228-178-7 heptyl viologen dibromide 4,4'-Bipyridinium, 1,1'-diheptyl-, bromide (1:2) N,N'-diheptyl-4,4'-dipyridinium dibromide 4,4'-BIPYRIDINIUM, 1,1'-DIHEPTYL-, DIBROMIDE DHBP dibromide DHBP (dibromide) |
| Description | DHBP dibromide is an inhibitor for calcium release and a muscle relaxant. |
|---|---|
| Related Catalog | |
| In Vitro | DHBP inhibits the calcium release induced by 2 mM caffeine and 2 μg/mL polylysine with an IC50 value of 5 μg/mL and 4 μg/mL, respectively. DHBP inhibits [3H]-ryanodine binding in a dose-dependent manner with an IC50 of 2.5 μg/mL and 90-100% inhibition at 20-30 μg/mL. Calcium uptake by SR is inhibited in the presence of caffeine and this inhibition is antagonized by concomitant addition of DHBP. Muscle twitches elicited by direct electrical muscle stimulation and contractions induced by either 10 mM caffeine or 1 fLM ryanodine are blocked by pretreatment with DHBP. DHBP blocks the calcium release from SR by direct interaction with the calcium release channel, also known as the ryanodine receptor[1]. |
| References |
| Melting Point | 285 °C (dec.)(lit.) |
|---|---|
| Molecular Formula | C24H38Br2N2 |
| Molecular Weight | 514.380 |
| Exact Mass | 512.140137 |
| PSA | 7.76000 |
| Storage condition | Store at RT |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
|
~%
6159-05-3 |
| Literature: Russian Journal of General Chemistry, , vol. 66, # 9 p. 1490 - 1496 |
|
~14%
6159-05-3 |
| Literature: Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 3 p. 367 - 372 |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |