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  • DC Chemicals Limited
  • China
  • Product Name: AC-55649
  • Price: $900.0/100mg $1800.0/250mg $3600.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

59662-49-6

59662-49-6 structure
59662-49-6 structure
  • Name: AC 55649
  • Chemical Name: 4-(4-octylphenyl)benzoic acid
  • CAS Number: 59662-49-6
  • Molecular Formula: C21H26O2
  • Molecular Weight: 310.43000
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
  • Create Date: 2018-08-09 15:27:32
  • Modify Date: 2024-01-09 12:03:11
  • AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.

Name 4-(4-octylphenyl)benzoic acid
Synonyms MFCD00157040
4-Octyl-4'-biphenylcarboxylic acid
8BCA
4-n-octylbiphenyl-4'-carboxylic acid
4'-Octylbiphenyl-4-carboxylic acid
octyldiphenylcarboxylic acid
4'-octyl-4-phenylbenzoic acid
4'-octyloxy-4-biphenylcarboxylic acid
Description AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.
Related Catalog
Target

RARβ2:6.9 (pEC50)

In Vitro AC-55649 is a potent, highly isoform-selective agonist at the human RARβ2 receptor, with a pEC50 of 6.9[1]. AC-55649 is a potent and selective activator of RARβ2 transcriptional activity[2].
References

[1]. Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J Med Chem. 2005 Dec 1;48(24):7517-9.

[2]. Piu F, et al. Identification of novel subtype selective RAR agonists. Biochem Pharmacol. 2005 Dec 19;71(1-2):156-62.

Density 1.037g/cm3
Boiling Point 462ºC at 760 mmHg
Molecular Formula C21H26O2
Molecular Weight 310.43000
Flash Point 216.9ºC
Exact Mass 310.19300
PSA 37.30000
LogP 5.95480
Index of Refraction 1.548
Storage condition 2-8℃
Hazard Statements H413
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2916399090
Precursor  1

DownStream  0

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%